#COVID19 and #dengue #coinfection in a returning #traveller (J Trav Med., abstract)

[Source: Journal of Travel Medicine, full page: (LINK). Abstract, edited.]

COVID-19 and dengue co-infection in a returning traveller

Loïc Epelboin, MD, PhD, Renaud Blondé, MD, Mathieu Nacher, MD, PhD, Patrice Combe, MD, Louis Collet, MD

Journal of Travel Medicine, taaa114, https://doi.org/10.1093/jtm/taaa114

Published: 13 July 2020

 

Abstract

In march 2020, a pandemic of respiratory infection due to the SARS-CoV2 is underway, dengue fever epidemics are at the same time present in many regions of the inter-equatorial zone. We report the first cases of covid19-dengue co-infection, which occurred in Mayotte, a French island in the Indian Ocean.

coronavirus, COVID-19, severe acute respiratory syndrome coronavirus 2, pandemic; dengue fever, tropical diseases, France, Western Europe, Mayotte; coinfection

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This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Keywords: SARS-CoV-2; COVID-19; Dengue fever; Mayotte.

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#Coinfection, co‐epidemics of #Covid19 and #Dengue in dengue endemic countries: a serious health concern (J Med Virol., abstract)

[Source: Journal of Medical Virology, full page: (LINK). Abstract, edited.]

Co‐infection, co‐epidemics of Covid‐19 and Dengue in dengue endemic countries: a serious health concern

Md. Asaduzzaman Miah,  Asmaul Husna

First published: 07 July 2020 | DOI:  https://doi.org/10.1002/jmv.26269

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/jmv.26269

 

Abstract

During the Covid‐19 pandemic, dengue cases have been increased in most of the dengue‐endemic countries in the world. Therefore, in these countries, both Covid‐19 and Dengue are occurring simultaneously. The dengue‐endemic countries are at the risk of possible co‐infection and co‐epidemics in where Covid‐19 and dengue disease are co‐existing, and the viruses are cocirculating. Thus, co‐infection and co‐epidemics trigger alert, especially for the health care professionals in the dengue‐endemic countries.

This article is protected by copyright. All rights reserved.

Keywords: SARS-CoV-2; COVID-19; Dengue fever.

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#Dengue and #COVID19, overlapping #epidemics? An Analysis from #Colombia (J Med Virol., abstract)

[Source: Journal of Medical Virology, full page: (LINK). Abstract, edited.]

Dengue and COVID‐19, overlapping epidemics? An Analysis from Colombia

Jaime A. Cardona‐Ospina,  Kovy Arteaga‐Livias,  Wilmer E. Villamil‐Gómez,  Carlos E. Pérez‐Díaz,  D. Katterine Bonilla‐Aldana,  Álvaro Mondragon‐Cardona,  Marco Solarte, Ernesto Martinez,  Jose Millan‐Oñate,  Eduardo López,  Pio López,  Juan‐Carlos Navarro, Luis Perez‐Garcia,  Euler Mogollon‐Rodriguez,  Alfonso J. Rodríguez‐Morales,  Alberto Paniz‐Mondolfi, …

First published: 19 June 2020 | DOI:  https://doi.org/10.1002/jmv.26194

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/jmv.26194

 

Abstract

Coronavirus Disease 2019 (COVID‐19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2), has rapidly spread throughout Latin America, a region swept by multiple previous and ongoing epidemics. There are significant concerns that the arrival of COVID‐19 is currently overlapping with other viruses, particularly dengue, in various endo‐epidemic regions across South America. In this report, we analyzed trends for both viral infections in Colombia during the first 20 epidemiological weeks of 2020. From January 1st to May 16th, 2020 (epidemiological weeks, EW, 1‐20), a total of 52,679 cases of dengue and 14,943 cases of COVID‐19 have been confirmed in Colombia. As both conditions may potentially lead to fatal outcomes, especially in patients with chronic co‐morbidities, overlapping infections and co‐occurrence may increase the number of patients requiring intensive care and mechanical ventilation. In regions such as Valle del Cauca, intensified preparation for such scenarios should be pondered, and further studies should be performed to address this critical issue in a timely matter.

This article is protected by copyright. All rights reserved.

Keywords: SARS-CoV-2; COVID-19; Dengue fever; Colombia.

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#COVID19 and #dengue virus co‐epidemics in #Pakistan: A dangerous combination for overburdened healthcare system (J Med Virol., abstract)

[Source: Journal of Medical Virology, full page: (LINK). Abstract, edited.]

COVID‐19 and dengue virus co‐epidemics in Pakistan: A dangerous combination for overburdened healthcare system

Aleena Haqqi,  Usman Ayub Awan,  Muhammad Ali,  Muhammad Arif Nadeem Saqib, Haroon Ahmed,  Muhammad Sohail Afzal

First published: 08 June 2020 | DOI:  https://doi.org/10.1002/jmv.26144

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/jmv.26144

 

Abstract

We have read recent articles regarding co‐epidemics/co‐infections of COVID‐19 and other infectious diseases 1‐4, these reports highlights the impact of co‐infections on the health care system. The recent pandemic of COVID‐19 caused by a novel severe acute respiratory syndrome coronavirus ‐ SARS‐CoV‐2 has taken 378K lives and has spread worldwide infecting over 6.3 million individuals.

This article is protected by copyright. All rights reserved.

Keywords: SARS-CoV-2; COVID-19; Dengue Fever; Pakistan.

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#Arboviral diseases and #COVID19 in #Brazil: Concerns regarding climatic, #sanitation and #endemic scenario (J Med Virol., abstract)

[Source: Journal of Medical Virology, full page: (LINK). Abstract, edited.]

Arboviral diseases and COVID‐19 in Brazil: Concerns regarding climatic, sanitation and endemic scenario

Victoria Stadler Tasca Ribeiro,  João Paulo Telles,  Felipe Francisco Tuon

First published: 28 May 2020 | DOI:  https://doi.org/10.1002/jmv.26079

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/jmv.26079

 

Abstract

Brazil is witnessing a massive increase of COVID‐19 cases and may face some difficulties, not only regarding to other respiratory pathogens, but also to other relevant issues parallelly occurring, for instance, the beggining of autumn and winter seasons, which provides a longer period with high transmissibility of respiratory viroses. Additionally, Brazil is localized in a geographical tropical area with relevant arboviral diseases, where Dengue fever presented highest incidence during March‐June, mainly at Southeast and Midwest regions, where probably it will occur overlapping curves of arboviruses and COVID‐19, which will overload our public health system. The main affected áreas by COVID‐19 in Brazil were the same that presented 66% of the Dengue fever cases in Brazil. Moreover, it is importante to highlight the difficulty found to distinguish Dengue fever and COVID‐19 and its implications, which present similar laboratorial and clinical characteristics. Besides that, it has been pointed out false‐positive results in serological tests for Dengue fever, which later were confirmed as COVID‐19. These issues demand urgent attention,once they culminate in serious and devastating impacts in the Brazilian health system, public health, and social conditions.

This article is protected by copyright. All rights reserved.

Keywords: SARS-CoV-2; COVID-19; Arbovirus; Dengue fever; Brazil.

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#Covert #COVID19 and false-positive #dengue #serology in #Singapore (Lancet Infect Dis., summary)

[Source: The Lancet Infectious Diseases, full page: (LINK). Summary, edited.]

Covert COVID-19 and false-positive dengue serology in Singapore

Gabriel Yan, Chun Kiat Lee, Lawrence T M Lam, Benedict Yan, Ying Xian Chua, Anita Y N Lim, Kee Fong Phang, Guan Sen Kew, Hazel Teng, Chin Hong Ngai, Li Lin, Rui Min Foo, Surinder Pada, Lee Ching Ng, Paul Anantharajah Tambyah

Published: March 04, 2020 / DOI: https://doi.org/10.1016/S1473-3099(20)30158-4

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Dengue and coronavirus disease 2019 (COVID-19) are difficult to distinguish because they have shared clinical and laboratory features.1, 2 We describe two patients in Singapore with false-positive results from rapid serological testing for dengue, who were later confirmed to have severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the causative virus of COVID-19.

(…)

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We declare no competing interests.

Keywords: SARS-CoV-2; COVID-19; Dengue fever; Diagnostic tests; Singapore.

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#Reciprocal immune #enhancement of #dengue and #Zika virus #infection in #human #skin (JCI Insight, abstract)

[Source: US National Library of Medicine, full page: (LINK). Abstract, edited.]

JCI Insight. 2020 Jan 7. pii: 133653. doi: 10.1172/jci.insight.133653. [Epub ahead of print]

Reciprocal immune enhancement of dengue and Zika virus infection in human skin.

Castanha PM, Erdos G, Watkins SC, Falo LD Jr, Marques ET, Barratt-Boyes SM.

 

Abstract

Dengue (DENV) and Zika viruses (ZIKV) are closely related mosquito-borne flaviviruses that co-circulate in tropical regions and constitute major threats to global human health. Whether preexisting immunity to one virus affects disease caused by the other during primary or secondary infections is unknown but is critical in preparing for future outbreaks and predicting vaccine safety. Using a human skin explant model, we show that DENV-3 immune sera increased recruitment and infection of Langerhans cells, macrophages and dermal dendritic cells following inoculation with DENV-2 or ZIKV. Similarly, ZIKV immune sera enhanced infection with DENV-2. Immune sera increased migration of infected Langerhans cells to dermis and emigration of infected cells out of skin. Heterotypic immune sera increased viral RNA in dermis almost tenfold and reduced the amount of virus required to infect a majority of myeloid cells by 100 to 1,000 fold. Enhancement was associated with cross-reactive IgG and induction of IL-10 expression and was mediated by both CD32 and CD64 Fcγ receptors. These findings reveal that preexisting heterotypic immunity greatly enhances DENV and ZIKV infection, replication and spread in human skin. This relevant tissue model will be valuable in assessing the efficacy and risk of dengue and Zika vaccines in humans.

KEYWORDS: Dendritic cells; Immunoglobulins; Immunology; Infectious disease; Macrophages

PMID: 31910161 DOI: 10.1172/jci.insight.133653

Keywords: Dengue fever; Zika Virus; ADE.

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#Risk of #dengue in Central #Africa: #Vector competence studies with #Aedes aegypti and Aedes albopictus (Diptera: Culicidae) populations and dengue 2 virus (PLOS Negl Trop Dis., abstract)

[Source: PLOS Neglected Tropical Diseases, full page: (LINK). Abstract, edited.]

OPEN ACCESS /  PEER-REVIEWED / RESEARCH ARTICLE

Risk of dengue in Central Africa: Vector competence studies with Aedes aegypti and Aedes albopictus (Diptera: Culicidae) populations and dengue 2 virus

Basile Kamgang , Marie Vazeille, Armel N. Tedjou, Theodel A. Wilson-Bahun, Aurélie P. Yougang, Laurence Mousson, Charles S. Wondji , Anna-Bella Failloux

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Published: December 30, 2019 / DOI: https://doi.org/10.1371/journal.pntd.0007985 / This is an uncorrected proof.

 

Abstract

Introduction

Dengue is the most important mosquito-borne diseases worldwide but was considered scarce in West-Central Africa. During the last decade, dengue outbreaks have increasingly been reported in urban foci in this region suggesting major epidemiological changes. However, in Central Africa where both vectors, Aedes aegypti and Aedes albopictus are well established, the role of each species in dengue transmission remains poorly investigated.

Methodology/Principal findings

Field-collected strains of Ae. aegypti and Ae. albopictus from different ecological settings in Central Africa were experimentally challenged with dengue 2 virus (DENV-2). Mosquitoes were analysed at 14- and 21-days post-infection. Analysis provide evidence that both Ae. aegypti and Ae. albopictus in Central Africa were able to transmit dengue virus with Ae. aegypti exhibiting a higher transmission rate. Unexpectedly, two Ae. aegypti populations from Bénoué and Maroua, in northern Cameroon, were not able to transmit DENV-2.

Conclusions/Significance

We conclude that both Ae. aegypti and Ae. albopictus are susceptible to DENV-2 and may intervene as active dengue vectors. These findings highlight the urgent need to plan a vector surveillance program and control methods against dengue vectors in Central Africa in order to prevent future outbreaks.

 

Author summary

Dengue virus (DENV) is a flavivirus mainly transmitted to humans through the bite of infected mosquitoes notably Aedes aegypti and Aedes albopictus. In Central Africa where both vectors, Ae. aegypti and Ae. albopictus are well established, the role of each species in dengue transmission remains poorly investigated. Here, we assessed the vector competence of Ae. aegypti and Ae. albopictus collected in different ecological settings in Central Africa to transmit dengue 2 virus (DENV-2). We provide evidence that both Ae. aegypti and Ae. albopictus in Central Africa were able to transmit dengue virus with Ae. aegypti exhibiting a higher transmission rate. These findings could increase the risk of dengue outbreak in the region and emphasize the need for a comprehensive vector surveillance program to prevent and preparedness for an intervention in case of outbreaks.

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Citation: Kamgang B, Vazeille M, Tedjou AN, Wilson-Bahun TA, Yougang AP, Mousson L, et al. (2019) Risk of dengue in Central Africa: Vector competence studies with Aedes aegypti and Aedes albopictus (Diptera: Culicidae) populations and dengue 2 virus. PLoS Negl Trop Dis 13(12): e0007985. https://doi.org/10.1371/journal.pntd.0007985

Editor: Duane J. Gubler, Duke-NUS GMS, SINGAPORE

Received: September 9, 2019; Accepted: December 10, 2019; Published: December 30, 2019

Copyright: © 2019 Kamgang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Data Availability: All relevant data are within the manuscript.

Funding: BK was funded by the Wellcome Trust, 204862/Z/16/Z (https://wellcome.ac.uk). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing interests: The authors have declared that no competing interests exist.

Keywords: Flavivirus; Dengue fever; Africa region; Mosquitoes; Aedes aegypti; Aedes albopictus.

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Full-Length #Genome #Sequence of a #Dengue serotype 1 virus isolate from a #traveller returning from #DRC to #Italy, July 2019 (Int J Infect Dis., abstract)

[Source: US National Library of Medicine, full page: (LINK). Abstract, edited.]

Int J Infect Dis. 2019 Dec 19. pii: S1201-9712(19)30496-5. doi: 10.1016/j.ijid.2019.12.023. [Epub ahead of print]

Full-Length Genome Sequence of a Dengue serotype 1 virus isolate from a traveller returning from Democratic Republic of Congo to Italy, July 2019.

Colavita F1, Vairo F2, Carletti F1, Boccardo C3, Ferraro F1, Iaiani G4, Al Moghazi S1, Galardo G3, Lalle E1, Selvaggi C1, Scognamiglio P1, Capobianchi MR1, Ippolito G1, Castilletti C1.

Author information: 1 National Institute for Infectious Diseases ‘Lazzaro Spallanzani’ IRCCS, 00149 Rome, Italy. 2 National Institute for Infectious Diseases ‘Lazzaro Spallanzani’ IRCCS, 00149 Rome, Italy. Electronic address: francesco.vairo@inmi.it. 3 Dipartimento di Emergenza e Accettazione, Policlinico Umberto 1, Rome, Italy. 4 Dipartimento di Malattie Infettive e Tropicali, Policlinico Umberto 1, Rome, Italy.

 

Abstract

We report the full-genome sequence of a Dengue serotype-1 virus (DENV-1) isolated from a traveller returning in July 2019 to Italy from Democratic Republic of Congo (DRC), which is currently affected by Ebola and measles outbreaks. The sequence shows high similarity with two 2013 strains isolated in Angola and China.

Copyright © 2019. Published by Elsevier Ltd.

KEYWORDS: Democratic Republic of Congo; Dengue virus; Full-genome sequence; Travel-associated infection

PMID: 31866548 DOI: 10.1016/j.ijid.2019.12.023

Keywords: Dengue fever; DRC; Italy.

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Association of #Allergic #Symptoms with #Dengue #Infection and #Severity: A Systematic Review and Meta-analysis (Virol Sin., abstract)

[Source: Virologica Sinica, full page: (LINK). Abstract, edited.]

Association of Allergic Symptoms with Dengue Infection and Severity: A Systematic Review and Meta-analysis

Authors: Nguyen Dang Kien, Amr Ehab El-Qushayri, Ali Mahmoud Ahmed, Adnan Safi, Sarch Abdel Mageed, Samar Muhammed Mehyar, Mohammad Rashidul Hashan, Sedighe Karimzadeh, Kenji Hirayama, Nguyen Tien Huy

RESEARCH ARTICLE / First Online: 21 October 2019

 

Abstract

The relationship between the severity of dengue infection and allergy is still obscure. We conducted an electronic search across 12 databases for relevant articles reporting allergic symptoms, dengue infection, and dengue classification. These studies were categorized according to dengue severity and allergy symptoms, and a meta-analysis was performed by pooling the studies in each category. Among the included 57 articles, pruritus was the most common allergic sign followed by non-specified allergy and asthma (28.6%, 13%, and 6.5%, respectively). Despite the reported significant association of dengue with pruritus and total IgE level (P < 0.05), in comparison with non-dengue cases and healthy controls, there was no association between the different severe dengue group with pruritus, skin allergy, food allergy or asthma. However, removing the largest study revealed a significant association between asthma with dengue hemorrhagic fever (DHF) rather than dengue fever (DF). In comparison with DF, DHF was associated with IgE positivity. Furthermore, specific-IgE level was higher in secondary DF rather than primary DF. There was a possible association between allergy symptoms and dengue severity progression. Further studies are needed to clarify this association.

Keywords: Dengue – Allergy – Severity – IgE – Asthma – Association

Nguyen Dang Kien, Amr Ehab El-Qushayri and Ali Mahmoud Ahmed have contributed equally to this work.

 

Electronic supplementary material

The online version of this article ( https://doi.org/10.1007/s12250-019-00165-6) contains supplementary material, which is available to authorized users.

 

Notes

Acknowledgements

We acknowledged the contributions of Nguyen Thi Huyen Trang (Hue University of Medicine and Pharmacy, Hue City, Vietnam), Nguyen Phuoc Long, Le Phi Hung, and Nguyen Thien Luan (University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam), Tran Thi Minh Hue (Hanoi Medical University, Vietnam) Doan Ngoc Dinh (Health Strategy and Policy Institute (HSPI),MoH Vietnam), Tran Dinh Trung (Da Nang University of Medical Technology and Pharmacy, Da Nang City, Vietnam) on the initial work of the study.

Author Contributions

NDK, AEE, AMA and NTH designed the experiments. NDK, AEE, AMA, AS, SAM, SMM, SK, MRH and KH collected the documents and summed up the data. NDK, AEE, AMA and NTH analyzed the data. NDK, AEE, AMA and NTH wrote the manuscript. All author read and approved the final manuscript.

 

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Animal and Human Rights Statement

This article does not contain any studies with human or animal subjects performed by any of the authors.

Keywords: Dengue fever; Allergy.

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