[Source: Journal of Medical Virology, full page: (LINK). Abstract, edited.]
Clinical analysis of pregnant women with 2019 novel coronavirus pneumonia
Siyu Chen, E Liao, Yong Shao
First published: 28 March 2020 | DOI: https://doi.org/10.1002/jmv.25789
Funded by National Natural Science Foundation of China (No: 81471473); Chongqing Health Planning Commission project for training talented medical professionals (No. 2015XMSB0001298 and No. 2019ZDXM055).
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/jmv.25789
To evaluate the pregnant women infected with coronavirus disease 2019 (COVID‐19) and provide help for clinical prevention and treatment.
All 5 cases of pregnant women confirmed COVID‐19 were collected among patients who admitted in Maternal and Child Hospital of Hubei Province between January 20 and February 10, 2020.
All patients, aging from 25 to 31 years old, had the gestational week from 38th weeks to 41st weeks. All pregnant women did not have an antepartum fever but developed a low‐grade fever (37.5‐38.5℃) within 24 hours after delivery. All patients had normal liver and renal function, two patients had elevated plasma levels of the myocardial enzyme. Unusual chest imaging manifestations, featured with ground‐grass opacity, were frequently observed in bilateral (3 cases) or unilateral lobe (2 cases) by computed tomography (CT) scan. All labors smoothly processed, the Apgar scores were 10 one and five minutes after delivery, no complications were observed in the newborn.
Pregnancy and perinatal outcomes of patients with COVID‐19 should receive more attention. It is probable that pregnant women diagnosed with COVID‐19 have no fever before delivery. Their primary initial manifestations were merely low‐grade postpartum fever or mild respiratory symptoms. Therefore, the protective measures are necessary on admission; the instant CT scan and real‐time reverse‐transcriptase polymerase‐chain‐reaction (RT‐PCR) assay should be helpful in early diagnosis and avoid cross‐infection on the occasion that patients have fever and other respiratory signs.
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Keywords: SARS-CoV-2; COVID-19; Pregnancy.