Novel #coronavirus disease (#Covid19): the first two #patients in the #UK with #p2p #transmission (J Infect., summary)

[Source: Journal of Infection, full page: (LINK). Abstract, edited.]

Journal of Infection / Available online 28 February 2020 / In Press, Journal Pre-proof / Letter to the Editor

Novel coronavirus disease (Covid-19): the first two patients in the UK with person to person transmission

Patrick J Lillie a, Anda Samson a, Ang Li b, Kate Adams a, Richard Capstick b, Gavin D Barlow a, c, Nicholas Easom a, Eve Hamilton b, Peter J Moss a, Adam Evans b, Monica Ivan a, PHE Incident Team d, Yusri Taha b, Christopher J A Duncan b,e, Matthias L Schmid b, the Airborne HCID Network f

{a} Department of Infection, Hull University Teaching Hospitals NHS Trust, Hull, United Kingdom; {b} Department of Infection & Tropical Medicine, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; {c} Hull York Medical School, University of York, United Kingdom4. National Infection Service; {d} PHE Incident Team, Public Health England, London NW9 5EQ, United Kingdom; {e} Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle University, United Kingdom; {f} Airborne HCID Network

Accepted 25 February 2020, Available online 28 February 2020.

DOI: https://doi.org/10.1016/j.jinf.2020.02.020

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Tang and colleagues reported in this journal their experience with COVID-19 disease1, the outbreak of which began in December 2019 in Wuhan, Hubei province, China2,3 with spread to 33 additional countries4, 5, 6, 7, 8 as of the 21st February 2020. Here we report the clinical features and outcome of the first two cases of disease caused by SARS-CoV-2 infection in the United Kingdom (UK) – the first imported and the second associated with probable person-to-person transmission within the UK. Public health management will be reported separately.

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Acknowledgements

We are grateful to the patients for providing their written informed consent to publish this report. Our thanks go to nursing, laboratory and medical colleagues in Hull University Teaching Hospitals NHS Trust and The Newcastle Upon Tyne Hospitals NHS Foundation Trust who contributed directly and indirectly to patient care, and to many colleagues in Public Health England and across the HCID network who contributed their time and expertise to the management of these cases. CJAD is supported by a Clinical Research Career Development Fellowship from the Wellcome Trust (211153/Z/18/Z).

Keywords: COVID-19; SARS-CoV-2; UK.

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Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.