#Genomic characterizations of #H4 subtype #avian #influenza viruses from live #poultry #markets in #Sichuan province of #China, 2014-2015 (Sci China Life Sci., abstract)

[Source: US National Library of Medicine, full page: (LINK). Summary, edited.]

Sci China Life Sci. 2018 Sep;61(9):1123-1126. doi: 10.1007/s11427-018-9327-4. Epub 2018 Jul 9.

Genomic characterizations of H4 subtype avian influenza viruses from live poultry markets in Sichuan province of China, 2014-2015.

Quan C1, Huang T2, Chen X2, Zhang J1, Wang Q3, Zhang C4, Zhang T5, Zhou L2, Shu L1, Long C5, Yang L6, Du X6, Zhao Y1, Liu P1, Song H7, Shi W8, Bi Y4, Lv Q2, Liu WJ9, Gao GF10,11,12.

Author information: 1 National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China. 2 Sichuan Center for Disease Control and Prevention, Chengdu, 610041, China. 3 School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai, 200032, China. 4 CAS Key Laboratory of Pathogenic Microbiology and Immunology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing, 100101, China. 5 Longquanyi Center for Disease Control and Prevention, Chengdu, 610000, China. 6 Chengdu Center for Disease Control and Prevention, Chengdu, 610041, China. 7 Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, China. 8 Key Laboratory of Etiology and Epidemiology of Emerging Infectious Diseases in Universities of Shandong, Taishan Medical College, Taian, 271000, China. 9 National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China. liujun@ivdc.chinacdc.cn. 10 National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China. gaof@im.ac.cn. 11 CAS Key Laboratory of Pathogenic Microbiology and Immunology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing, 100101, China. gaof@im.ac.cn. 12 Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, China. gaof@im.ac.cn.

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Summary

Dear Editor, Avian influenza viruses (AIVs) have posed a serious threat to poultry production and public health. To date, more than fourteen AIV subtypes that are able to infect human beings have been documented. Also, it is suggested that new subtypes may be reported in the future, owing to the migration of wild birds and live poultry transportation (Gao, 2018). Poultry may act as a potential incubator for novel subtypes of avian influenza virus (Bi et al., 2016a; Bi et al., 2016b; Liu et al., 2014a; Su et al., 2017). Up to date, the H7N9 AIV emerged in February 2013 has caused 1,567 human cases, with a fatality rate of 39.2% (http://www.who.int/influenza/human_animal_interface/Influenza_Summary_IRA_HA_interface_02_03_2018.pdf?ua=1). Genetic analysis has demonstrated that the N9 gene derived from migratory birds, the H7 gene from ducks, and the internal genes from H9N2 virus in chickens reassorted to generate the novel H7N9 virus (Liu et al., 2014a; Liu et al., 2014b; Su et al., 2015). Notably, the majority of human infections with H7N9 AIV had a prior exposure history to live poultry markets (LPMs) (Quan et al., 2018; Tang and Wang, 2017; Xiao et al., 2017).

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PMID: 29995198 DOI: 10.1007/s11427-018-9327-4 [Indexed for MEDLINE]

Keywords: Avian Influenza; H4; Poultry; Sichuan; China; Live poultry markets.

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Detection of #plasmid-mediated #tigecycline-resistant gene tet(X4) in #Escherichia coli from #pork, #Sichuan and #Shandong Provinces, #China, February 2019 (Euro Surveill., abstract)

[Source: Eurosurveillance, full page: (LINK). Abstract, edited.]

Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, Sichuan and Shandong Provinces, China, February 2019

Li Bai1,2,3, Pengcheng Du3,4, Yinju Du5, Honghu Sun1,2,6, Pei Zhang1,2, Yuping Wan6, Qi Lin6, Séamus Fanning1,2,7, Shenghui Cui8, Yongning Wu1,2

Affiliations: 1 Key Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, Beijing, People’s Republic of China; 2 Food Safety Research Unit of Chinese Academy of Medical Sciences, China National Center for Food Safety Risk Assessment, Beijing, People’s Republic of China; 3 These authors contributed equally to this work; 4 Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, and Beijing Key Laboratory of Emerging Infectious Diseases, Beijing, People’s Republic of China; 5 Center for disease control and prevention of Liaocheng city, Liaocheng, People’s Republic of China; 6 Chengdu institute for Food and Drug Control, Chengdu, People’s Republic of China; 7 UCD-Centre for Food Safety, School of Public Health, Physiotherapy and Sports Science, University College Dublin, Belfield, Dublin, Ireland; 8 Department of Food Science, National Institutes for Food and Drug Control, Beijing, People’s Republic of China

Correspondence:  Yongning Wu

Citation style for this article: Bai Li, Du Pengcheng, Du Yinju, Sun Honghu, Zhang Pei, Wan Yuping, Lin Qi, Fanning Séamus, Cui Shenghui, Wu Yongning. Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, Sichuan and Shandong Provinces, China, February 2019. Euro Surveill.2019;24(25):pii=1900340. https://doi.org/10.2807/1560-7917.ES.2019.24.25.1900340

Received: 29 May 2019;   Accepted: 20 Jun 2019

 

Abstract

The plasmid-mediated high-level tigecycline resistance gene, tet(X4), was detected in seven Escherichia coli isolates from pork in two Chinese provinces. Two isolates belonged to the epidemic spreading sequence type ST101. Tet(X4) was adjacent to ISVsa3 and concurrent with floR in all seven isolates. In addition to IncFIB, the replicon IncFII was found to be linked to tet(X4). This report follows a recent detection of tet(X3)/(X4) in E. coli from animals and humans in China.

©  This work is licensed under a Creative Commons Attribution 4.0 International License.

Keywords: Antibiotics; Drugs Resistance; Tigecycline; Plasmids; Pigs; E. Coli; Food Safety; China; Sichuan; Shandong.

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