[Source: Journal of Antimicrobial Chemotherapy, full page: (LINK). Abstract, edited.]
Co-occurrence of mcr-1 and mcr-3 genes in a single Escherichia coli in New Zealand
Julie Creighton, Trevor Anderson, Julia Howard, Kristin Dyet, Xiaoyun Ren,Joshua Freeman
Journal of Antimicrobial Chemotherapy, dkz311, https://doi.org/10.1093/jac/dkz311
Published: 24 July 2019
Issue Section: Research letter
The discovery of the plasmid-mediated colistin resistance gene mcr-1, first identified in 2015 among both clinical and animal isolates in China, raised concerns about pan-resistant bacteria.1 A plethora of publications quickly followed, suggesting mcr-1 was already established in many countries and across many continents, in various bacterial species, on a variety of plasmids types, and in bacteria isolated from diverse animal species, environmental sources and human health settings.2 Furthermore, several other mcr-like genes and gene variants have since been discovered.2,3
Colistin is among a diminishing group of antimicrobial agents available for…
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Keywords: Antibiotics; Drugs Resistance; Colistin; E. Coli; New Zealand.