[Source: Thorax, full page: (LINK). Abstract, edited.]
Association between particulate matter air pollution and lung cancer
Zhenyu Zhang 1, Dawei Zhu 2, Bin Cui 3, Ruoxi Ding 4, Xuefeng Shi 5, Ping He 2
Author affiliations: 1 Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA; 2 China Center for Health Development Studies, Peking University, Beijing, China; 3 School of Public Health, Peking University, Beijing, China; 4 Institute of Population Research, Peking University, Beijing, China; 5 School of Management, Beijing University of Chinese Medicine, Beijing, China
Correspondence to Professor Ping He, China Center for Health Development Studies, Peking University, Beijing 100191, China; firstname.lastname@example.org; Professor Xuefeng Shi; email@example.com
Long-term exposure to particulate matter 2.5 μm (PM2.5) air pollution is associated with an increased risk of lung cancer. However, the evidence is limited in low-income and middle-income countries. We estimated the association between the incidence of lung cancer and PM2.5 air pollution exposure in the Urban Employee Basic Medical Insurance (UEBMI) beneficiaries in China. A total of 16 483 new lung cancer cases diagnosed from 12 966 137 UEBMI beneficiaries from 36 cities between 2013 and 2016. The relative risk for lung cancer associated with a 10 µg/m3 increase in 3-year PM2.5 exposure was 1.12 (95% CI 1.00 to 1.26). The population attributable risk estimated for a reduction in PM2.5 concentration to 35 µg/m3 corresponded to a decrease of 14% in cases of lung cancer. Reducing PM2.5 air pollution has a significant public health benefit.
XS and PH are joint senior authors.
ZZ and DZ contributed equally.
This work was supported by the Peking University’s Start-up Fund (BMU2018YJ004)
Patient consent for publication
The study was deemed as exempt from ethical approval by the institutional review board of the Beijing University of Chinese medicine (No.2019BZHYLL0201).
Provenance and peer review
Not commissioned; externally peer reviewed.
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Keywords: Environmental pollution; Cancer; China.