#Coronaviruses: #Genome Structure, #Replication, and #Pathogenesis (J Med. Virol., abstract)

[Source: US National Library of Medicine, full page: (LINK). Abstract, edited.]

Coronaviruses: Genome Structure, Replication, and Pathogenesis

Yu Chen 1, Qianyun Liu 1, Deyin Guo 2

Affiliations: 1 State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, P. R. China. 2 Center for Infection & Immunity Study, School of Medicine, Sun Yat-sen University, Guangzhou, P. R. China.

PMID: 31967327 DOI: 10.1002/jmv.25681



The recent emergence of a novel coronavirus (2019-nCoV), which caused an outbreak of unusual viral pneumonia in tens of people in Wuhan, a central city of China, restated the risk of coronaviruses posed to public health. In this mini-review, we give a brief introduction of the general features of coronaviruses and describe various diseases caused by different coronaviruses in humans and animals. This review will help understand the biology and potential risk of coronaviruses that exist in richness in wildlife such as bats.

Keywords: Coronavirus; Epidemiology; Pathogenesis; Respiratory tract; Virus classification; Zoonoses.

This article is protected by copyright. All rights reserved.

Keywords: Coronavirus; Wildlife; 2019-nCoV.


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Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.