#Seroprevalence of #SFTS #Phlebovirus in Domesticated #Deer in South #Korea (Virol Sin., abstract)

[Source: Virologica Sinica, full page: (LINK). Abstract, edited.]

Seroprevalence of Severe Fever with Thrombocytopenia Syndrome Phlebovirus in Domesticated Deer in South Korea

Authors: Min-Ah Yu, Kwang-Min Yu, Su-Jin Park, Young-Il Kim, Norbert John Robles, Young-Jae Si, Eun-Ha Kim, Hyeok-Il Kwon, Hye Won Jeong, Min-Suk Song, Seok-Yong Kim, Young Ki Choi

Research Article / First Online: 25 June 2019

 

Abstract

Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) has a wide host range. Not only has it been found in humans, but also in many wild and domesticated animals. The infection of breeding deer on farms is a particularly worrisome public health concern due to the large amount of human contact and the diverse use of deer products, including raw blood. To investigate the prevalence of breeding domesticated deer, we examined the SFTSV infection rate on deer farms in South Korea from 2015 to 2017. Of the 215 collected blood samples, 0.9% (2/215) were found to be positive for viral RNA by PCR, and sequence analysis showed the highest homology with the KADGH human isolate. Both SFTSV-specific recombinant N and Gn protein-based ELISAs revealed that 14.0% (30/215) and 7.9% (17/215) of collected blood specimens were positive for SFTSV antibody. These results demonstrate that the breeding farm deer are exposed to SFTSV and could be a potential infection source for humans through direct contact or consumption of byproducts.

Keywords: Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) – Breeding deer – Seroprevalence – South Korea

 

Notes

Acknowledgements

We thank all involved staffs in the diagnosis of SFTS during this study. We thank veterinarians at Sejeong Farms for collecting the samples. This work was supported by the Ministry of Health & Welfare (government—wide R&D fund project for infectious disease research (HG18C0029).

Author Contributions

M-AY and YKC conceptualized the study. M-AY, KMY, S-JP, Y-IK, NJR, Y-JS, E-HK, and H-IK, conducted the investigation. HWJ, M-SS, S-YK and YKC wrote the paper.

 

Compliance with Ethical Stanadards

Conflict of interest

The authors do not have any competing interests to declare.

Animal and Human Rights Statement

This work was supported by the Ministry of Health & Welfare (government – wide R&D fund project for infectious disease research (HG18C0029). Deer serum samples for the study were collected with the deer owner’s approval, and the experiments were conducted under the guidelines of the Chungbuk National University.

Keywords: SFTS; Phlebovirus; Livestock; Deers; S. Korea.

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Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.