#Trends in #Incidence and Stage at #Diagnosis of #Colorectal #Cancer in Adults Aged 40 Through 49 Years, 1975-2015 (JAMA, abstract)

[Source: JAMA, full page: (LINK). Abstract, edited.]

Research Letter / May 21, 2019

Trends in Incidence and Stage at Diagnosis of Colorectal Cancer in Adults Aged 40 Through 49 Years, 1975-2015

Reinier G. S. Meester, PhD1; Ajitha Mannalithara, PhD1; Iris Lansdorp-Vogelaar, PhD2; et alUri Ladabaum, MD, MS1

Author Affiliations: 1 Stanford University School of Medicine, Stanford, California; 2 Department of Public Health, Erasmus University Medical Center, Rotterdam, the Netherlands

JAMA. 2019;321(19):1933-1934. doi:10.1001/jama.2019.3076



Evidence suggests that incidence of colorectal cancer (CRC) is increasing among adults younger than 50 years in the United States.1 The underlying causes of the increased incidence are unclear. If the increase is the result of earlier detection due to increased use of colonoscopy, earlier stage at diagnosis would be expected, whereas if the increased incidence is the result of true increases in risk, relatively later stage at diagnosis would be expected. We investigated trends in CRC incidence by stage in adults younger than 50 years. We focused our study on adults aged 40 through 49 years, who account for almost 3 of 4 young-onset cases.

Keywords: Cancer; USA.


Published by

Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.