[Source: Journal of Antimicrobial Chemotherapy, full page: (LINK). Abstract, edited.]
Emergence of mcr-8.2-bearing Klebsiella quasipneumoniae of animal origin
Xiaorong Yang, Li Liu, Zhiqiang Wang, Li Bai, Ruichao Li
Journal of Antimicrobial Chemotherapy, dkz213, https://doi.org/10.1093/jac/dkz213
Published: 16 May 2019
The emergence of plasmid-mediated mcr-1, conferring resistance to colistin, which is considered as a last-resort drug to treat carbapenem-resistant Enterobacteriaceae (CRE) infections, poses a severe public health concern.1 Eight different mcr genes mainly mediated by plasmids were identified within 3 years after the reporting of mcr-1 in late 2015.1,2,Klebsiella pneumoniae is a well-known bacterium causing life-threatening infections, especially in neonates, the elderly and immunocompromised individuals.3 The mcr-1, mcr-3, mcr-7 and mcr-8 genes have been detected in K. pneumoniae recently.2,4,Klebsiella quasipneumoniae, which is found in animals and…
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Keywords: Antibiotics; Drugs Resistance; Colistin; Klebsiella pneumoniae; MCR8.