Emergence of #mcr-8.2-bearing #Klebsiella quasipneumoniae of #animal origin (J Antimicrob Chemother., abstract)

[Source: Journal of Antimicrobial Chemotherapy, full page: (LINK). Abstract, edited.]

Emergence of mcr-8.2-bearing Klebsiella quasipneumoniae of animal origin

Xiaorong Yang, Li Liu, Zhiqiang Wang, Li Bai, Ruichao Li

Journal of Antimicrobial Chemotherapy, dkz213, https://doi.org/10.1093/jac/dkz213

Published: 16 May 2019



The emergence of plasmid-mediated mcr-1, conferring resistance to colistin, which is considered as a last-resort drug to treat carbapenem-resistant Enterobacteriaceae (CRE) infections, poses a severe public health concern.1 Eight different mcr genes mainly mediated by plasmids were identified within 3 years after the reporting of mcr-1 in late 2015.1,2,Klebsiella pneumoniae is a well-known bacterium causing life-threatening infections, especially in neonates, the elderly and immunocompromised individuals.3 The mcr-1, mcr-3, mcr-7 and mcr-8 genes have been detected in K. pneumoniae recently.2,4,Klebsiella quasipneumoniae, which is found in animals and…



© The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Keywords: Antibiotics; Drugs Resistance; Colistin; Klebsiella pneumoniae; MCR8.



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I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.

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