#WNV and #Usutu Virus #Infections and Challenges to #Blood #Safety in the #EU (Emerg Infect Dis., abstract)

[Source: US Centers for Disease Control and Prevention (CDC), Emerging Infectious Diseases Journal, full page: (LINK). Abstract, edited.]

Volume 25, Number 6—June 2019 / Perspective

West Nile and Usutu Virus Infections and Challenges to Blood Safety in the European Union

Dragoslav Domanović  , Celine M. Gossner, Ryanne Lieshout-Krikke, Wolfgang Mayr, Klara Baroti-Toth, Alina Mirella Dobrota, Maria Antonia Escoval, Olaf Henseler, Christof Jungbauer, Giancarlo Liumbruno, Salvador Oyonarte, Constantina Politis, Imad Sandid, Miljana Stojić Vidović, Johanna J. Young, Inês Ushiro-Lumb, and Norbert Nowotny

Author affiliations: European Centre for Disease Prevention and Control, Solna, Sweden (D. Domanović, C.M. Gossner, J.J. Young); European Blood Alliance, Amsterdam, the Netherlands (R. Lieshout-Krikke); Austrian Red Cross, Vienna, Austria (W. Mayr, C. Jungbauer); National Competent Authority for Blood, Budapest, Hungary (K. Baroti-Toth); National Competent Authority for Blood, Bucharest, Romania (A.M. Dobrota); National Competent Authority for Blood, Lisbon, Portugal (M.A. Escoval); Paul Ehrlich Institute, Langen, Germany (O. Henseler); Italian National Blood Centre, National Institute of Health, Rome, Italy (G. Liumbruno); National Competent Authority for Blood, Madrid, Spain (S. Oyonarte); Hellenic Center for Disease Control and Prevention (KEELPNO), Athens, Greece (C. Politis); National Competent Authority for Blood, Paris, France (I. Sandid); Croatian Institute for Transfusion Medicine, Zagreb, Croatia (M.S. Vidović); National Health Service Blood and Transplant (NHSBT), London, UK (I. Ushiro-Lumb); University of Veterinary Medicine, Vienna, Austria (N. Nowotny); Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates (N. Nowotny)

 

Abstract

West Nile virus (WNV) and Usutu virus (USUV) circulate in several European Union (EU) countries. The risk of transfusion-transmitted West Nile virus (TT-WNV) has been recognized, and preventive blood safety measures have been implemented. We summarized the applied interventions in the EU countries and assessed the safety of the blood supply by compiling data on WNV positivity among blood donors and on reported TT-WNV cases. The paucity of reported TT-WNV infections and the screening results suggest that blood safety interventions are effective. However, limited circulation of WNV in the EU and presumed underrecognition or underreporting of TT-WNV cases contribute to the present situation. Because of cross-reactivity between genetically related flaviviruses in the automated nucleic acid test systems, USUV-positive blood donations are found during routine WNV screening. The clinical relevance of USUV infection in humans and the risk of USUV to blood safety are unknown.

Keywords: Usutu virus; WNV; Blood safety; EU.

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Published by

Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.

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