[Source: Journal of Antimicrobial Chemotherapy, full page: (LINK). Abstract, edited.]
A novel small tet(T)–tet(L)–aadD-carrying plasmid from MRSA and MSSA ST9 isolates of swine origin
Nansong Jiang, Jun Li, Andrea T Feßler, Yang Wang, Stefan Schwarz, Congming Wu
Journal of Antimicrobial Chemotherapy, dkz177, https://doi.org/10.1093/jac/dkz177
Published: 03 May 2019
Staphylococcus aureus, especially methicillin-resistant isolates, are major pathogens of humans and animals.1 Plasmids play a key role in the dissemination of antimicrobial resistance genes within the gene pool to which staphylococci and other Firmicutes have access.2 Tetracycline is one of the most commonly used antimicrobial agents in veterinary medicine and food animal production. The tetracycline resistance gene tet(L) was often identified on plasmids of S. aureus, particularly among those of livestock-associated MRSA (LA-MRSA) of ST398.3 In contrast, the tetracycline resistance gene tet(T) has only been reported in a few streptococcal and enterococcal strains.4 As…
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Keywords: Antibiotics; Drugs Resistance; Staphylococcus aureus; MRSA; Tetracycline; Pigs.