#Detection in #Greece of a #clinical #Enterococcus faecium isolate carrying the novel #oxazolidinone #resistance gene poxtA (J Antimicrob Chemother., abstract)

[Source: Journal of Antimicrobial Chemotherapy, full page: (LINK). Abstract, edited.]

Detection in Greece of a clinical Enterococcus faeciumisolate carrying the novel oxazolidinone resistance gene poxtA

Costas C Papagiannitsis, Katerina Tsilipounidaki, Ergina Malli, Efi Petinaki

Journal of Antimicrobial Chemotherapy, dkz155, https://doi.org/10.1093/jac/dkz155

Published: 22 April 2019



Oxazolidinones possess potent activity against Gram-positive pathogens such as VRE. Soon after their introduction into clinical practice, linezolid-resistant enterococcal isolates were reported.1 Resistance of enterococci to oxazolidines is mainly associated with mutations in 23S rRNA genes and L3 and L4 ribosomal proteins.2 Additionally, transferable resistance determinants including the cfr, optrAand poxtA genes have also emerged.3–5 Here we report, to the best of our knowledge, the first detection of a poxtA-positive Enterococcus faecium strain isolated in Greece.

…E. faecium isolate (Efa-955) was recovered, in 2018, from a urine sample of a patient treated in the University Hospital…



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This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Keywords: Antibiotics; Drugs Resistance; Linezolid; Enterococcus faecium; Greece.


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Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.