[Source: Journal of Antimicrobial Chemotherapy, full page: (LINK). Abstract, edited.]
Salmonella harbouring the mcr-1 gene isolated from food in China between 2012 and 2016
Yujie Hu, Séamus Fanning, Xin Gan, Chang Liu, Scott Nguyen, Meimei Wang, Wei Wang, Tao Jiang, Jin Xu, Fengqin Li
Journal of Antimicrobial Chemotherapy, dky496, https://doi.org/10.1093/jac/dky496
Published: 02 January 2019
In November 2015, plasmid-mediated transferable colistin resistance encoded by the mcr-1 gene in Escherichia coli and Klebsiella pneumonia isolates was reported in China with a high rate of in vitro horizontal transfer (10−1–10−3 cells per recipient cell by conjugation).1 At that time, the mcr-1 gene had already been identified in >30 countries across five continents, with novel mcr-2, mcr-3, mcr-4 and mcr-5 genes being reported subsequently.2–5 Recently, a surveillance study was performed on mainland China to investigate the prevalence of the mcr-1 gene in foodborne Salmonella isolates isolated from various food matrices and others collected…
Issue Section: Research letter
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Keywords: Food Safety; Antibiotics; Drugs Resistance; MCR1; Colistin; Salmonella spp.