[Source: US Centers for Disease Control and Prevention (CDC), Emerging Infectious Diseases Journal, full page: (LINK). Abstract, edited.]
Volume 24, Number 11—November 2018 / Research
Candida auris in South Africa, 2012–2016
Nelesh P. Govender , Rindidzani E. Magobo, Ruth Mpembe, Mabatho Mhlanga, Phelly Matlapeng, Craig Corcoran, Chetna Govind, Warren Lowman, Marthinus Senekal, and Juno Thomas
Author affiliations: National Health Laboratory Service, Johannesburg, South Africa (N.P. Govender, R.E. Magobo, R. Mpembe, M. Mhlanga, P. Matlapeng, J. Thomas); University of the Witwatersrand, Johannesburg (N.P. Govender, R.E. Magobo, W. Lowman); Ampath Laboratories, Pretoria, South Africa (C. Corcoran); Lancet Laboratories, Durban, South Africa (C. Govind); Vermaak and Partners Pathologists, Johannesburg/Cape Town, South Africa (W. Lowman, M. Senekal)
To determine the epidemiology of Candida auris in South Africa, we reviewed data from public- and private-sector diagnostic laboratories that reported confirmed and probable cases of invasive disease and colonization for October 2012–November 2016. We defined a case as a first isolation of C. auris from any specimen from a person of any age admitted to any healthcare facility in South Africa. We defined probable cases as cases where the diagnostic laboratory had used a nonconfirmatory biochemical identification method and C. haemulonii was cultured. We analyzed 1,692 cases; 93% were from private-sector healthcare facilities, and 92% of cases from known locations were from Gauteng Province. Of cases with available data, 29% were invasive infections. The number of cases increased from 18 (October 2012–November 2013) to 861 (October 2015–November 2016). Our results show a large increase in C. auris cases during the study period, centered on private hospitals in Gauteng Province.
Keywords: Candida auris; Nosocomial Outbreaks; South Africa.