Novel #mcr-5.3 variant in a CTX-M-8-producing #Escherichia coli ST711 isolated from an infected #horse (J Antimicrob Chemother., abstract)

[Source: Journal of Antimicrobial Chemotherapy, full page: (LINK). Abstract, edited.]

Novel mcr-5.3 variant in a CTX-M-8-producing Escherichia coli ST711 isolated from an infected horse

Miriam R Fernandes, Louise Cerdeira, Meire M Silva, Fábio P Sellera, Maria Muñoz, Felicio G Junior, Sergio S Azevedo, Pablo Power, Gabriel Gutkind, Nilton Lincopan

Journal of Antimicrobial Chemotherapy, dky341,

Published: 07 September 2018



Following the first description of the mobile phosphoethanolamine transferase gene mcr-1, responsible for transferable colistin resistance in Enterobacteriaceae of human and animal origin, a rapid dissemination and emergence of novel mcr variants has been globally described.1–5 

In this regard, two recent reports published in JAC have documented the identification of novel mcr-5 and mcr-5.2 gene variants in d-tartrate fermenting Salmonella enterica subsp. enterica serovar Paratyphi B and Escherichia coli from food and food-producing animals, respectively, in Germany.3,4

Interestingly, mcr-5 has also been identified in E. coli isolates from diseased pigs in Japan6 and from animals…


Issue Section: Research letter

© The Author(s) 2018. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email:

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (

Keywords: Antibiotics; Drugs Resistance; Colistin; MCR5; Horses.



Published by


I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum ( in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s