[Source: Journal of Antimicrobial Chemotherapy, full page: (LINK). Abstract, edited.]
Novel mcr-5.3 variant in a CTX-M-8-producing Escherichia coli ST711 isolated from an infected horse
Miriam R Fernandes, Louise Cerdeira, Meire M Silva, Fábio P Sellera, Maria Muñoz, Felicio G Junior, Sergio S Azevedo, Pablo Power, Gabriel Gutkind, Nilton Lincopan
Journal of Antimicrobial Chemotherapy, dky341, https://doi.org/10.1093/jac/dky341
Published: 07 September 2018
Following the first description of the mobile phosphoethanolamine transferase gene mcr-1, responsible for transferable colistin resistance in Enterobacteriaceae of human and animal origin, a rapid dissemination and emergence of novel mcr variants has been globally described.1–5
In this regard, two recent reports published in JAC have documented the identification of novel mcr-5 and mcr-5.2 gene variants in d-tartrate fermenting Salmonella enterica subsp. enterica serovar Paratyphi B and Escherichia coli from food and food-producing animals, respectively, in Germany.3,4
Interestingly, mcr-5 has also been identified in E. coli isolates from diseased pigs in Japan6 and from animals…
Issue Section: Research letter
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Keywords: Antibiotics; Drugs Resistance; Colistin; MCR5; Horses.