#Obesity Increases the #Duration of #Influenza A Virus #Shedding in Adults (J Infect Dis., abstract)

[Source: Journal of Infectious Diseases, full page: (LINK). Abstract, edited.]

Obesity Increases the Duration of Influenza A Virus Shedding in Adults

Hannah E Maier, Roger Lopez, Nery Sanchez, Sophia Ng, Lionel Gresh, Sergio Ojeda, Raquel Burger-Calderon, Guillermina Kuan, Eva Harris, Angel Balmaseda, Aubree Gordon

The Journal of Infectious Diseases, jiy370, https://doi.org/10.1093/infdis/jiy370

Published: 02 August 2018

 

Abstract

Epidemiologic studies indicate that obesity increases the risk of severe complications and death from influenza virus infections, especially in elderly individuals. This work investigates the effect of obesity on the duration of viral shedding within household transmission studies in Managua, Nicaragua, over 3 seasons (2015–2017). Symptomatic obese adults were shown to shed influenza A virus 42% longer than nonobese adults (adjusted event time ratio [ETR], 1.42; 95% confidence interval [CI], 1.06–1.89); no association was observed with influenza B virus shedding duration. Even among paucisymptomatic and asymptomatic adults, obesity increased the influenza A shedding duration by 104% (adjusted ETR, 2.04; 95% CI, 1.35–3.09). These findings suggest that obesity may play an important role in influenza transmission.

Influenza virus, obesity, viral shedding, paucisymptomatic, asymptomatic, transmission, household, epidemiology, public health

Topic: obesity – influenza – adult – influenza a virus – nicaragua – orthomyxoviridae – virus shedding

Issue Section: Brief Report

Keywords: Influenza A; Seasonal Influenza; Obesity; Nicaragua.

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gimi69

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.

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