[Source: US National Library of Medicine, full page: (LINK). Abstract, edited.]
Arch Virol. 2018 Jul;163(7):1955-1960. doi: 10.1007/s00705-018-3818-6. Epub 2018 Mar 20.
Isolation and characterization of an avian-origin H3N8 canine influenza virus from a dog in eastern China.
Cao X1, Liu X2, Zheng S3, Xu L4, Wu H5, Liu J6.
Author information: 1 Dezhou College, Dezhou, 253023, Shandong, China. firstname.lastname@example.org. 2 Shandong Vocational Animal Science and Veterinary College, Weifang, 261061, Shandong, China. 3 Dezhou College, Dezhou, 253023, Shandong, China. 4 Animal Husbandry and Veterinary Institute, Zhejiang Academy of Agricultural Science, Hangzhou, 310021, Zhejiang, China. 5 State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, Zhejiang, China. 6 Animal Hospital of Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Previous studies have shown that dogs are susceptible to influenza A viruses, and the close contact between dogs and humans poses a threat to public health. In 2015, a novel H3N8 influenza virus was isolated from a dog in eastern China. This strain was characterized by whole-genome sequencing with subsequent phylogenetic analysis and genetic comparison and found to be most closely related to avian influenza viruses co-circulating in China. It was able to replicate in mice without prior adaptation. The continued circulation of this novel H3N8 influenza virus in dogs could endanger other mammalian species.
PMID: 29556821 DOI: 10.1007/s00705-018-3818-6 [Indexed for MEDLINE]
Keywords: Avian Influenza; Canine Avian Influenza; H3N8; China; Dogs.