#CTX-M-55, #MCR1 and fosA producing multi #resistant #Ecoli in a #pediatric #infection in #France (Antimicrob Agents Chemother., abstract)

[Source: Antimicrobial Agents and Chemotherapy, full page: (LINK). Abstract, edited.]

CTX-M-55, MCR-1 and fosA producing multi-resistant E. coli in a pediatric infection in France

André Birgy1,  Fouad Madhi2,3,4, Julien Hogan5, Catherine Doit6, Jean Gaschignard7, Marion Caseris7,  Philippe Bidet1, Robert Cohen3,4,8,9 and Stéphane Bonacorsi1*

Author Affiliations: 1 IAME, UMR 1137, INSERM, Université Paris Diderot, Sorbonne Paris Cité, AP-HP, Service de Microbiologie, Hôpital Robert Debré, AP-HP, Paris, France; 2 Service de Pédiatrie Générale, Centre Hospitalier Intercommunal de Créteil, France; 3 Groupe de Pathologie Infectieuse Pédiatrique (GPIP), Paris, France; 4 Centre de Recherche Clinique, Centre Hospitalier Intercommunal de Créteil, France; 5 Service de Néphrologie, Hôpital Robert Debré, AP-HP, Paris, France; 6 Service de Microbiologie, Centre National de Référence associé Escherichia coli, Hôpital Robert Debré, AP-HP, Paris, France; 7 Service de Pédiatrie Générale, Hôpital Robert-Debré, AP-HP, Paris, France; 8 Association Clinique Thérapeutique Infantile du Val de Marne (ACTIV), Saint Maur des Fossés, France; 9 Unité Court Séjour, Petits Nourrisson, Service de Néonatologie, Centre Hospitalier Intercommunal de Créteil, France



Horizontally transferable plasmid-mediated mcr-1 gene encoding a phosphoethanolamine transferase conferring resistance to colistin in multiresistant pathogen may lead to therapeutic impasse.…



*Corresponding authors: Stéphane Bonacorsi (SB), MD, PhD, Hôpital Robert-Debré (APHP),48 Boulevard Sérurier F75019 Paris, France (stephane.bonacorsi@aphp.fr)

Copyright © 2018 American Society for Microbiology. All Rights Reserved.

Keywords: Antibiotics; Drugs Resistance; MCR1; E. Coli; France.


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Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.