[Source: PLoS Neglected Tropical Diseases, full page: (LINK). Extract, edited.]
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Differential virulence between Asian and African lineages of Zika virus
Yannick Simonin , Debby van Riel, Philippe Van de Perre, Barry Rockx , Sara Salinas
Published: September 21, 2017 / DOI: https://doi.org/10.1371/journal.pntd.0005821
Citation: Simonin Y, van Riel D, Van de Perre P, Rockx B, Salinas S (2017) Differential virulence between Asian and African lineages of Zika virus. PLoS Negl Trop Dis 11(9): e0005821. https://doi.org/10.1371/journal.pntd.0005821
Editor: Rebecca Rico-Hesse, Baylor College of Medicine, UNITED STATES
Published: September 21, 2017
Copyright: © 2017 Simonin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: This work was funded by REACting (https://www.inserm.fr/zoom/reacting-une-approche-multidisciplinaire-pourrelever-le-defi-des-crises-epidemiques). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests: The authors have declared that no competing interests exist.
Zika virus (ZIKV) is a small enveloped positive-sense single-stranded RNA virus belonging to the genus Flavivirus of the Flaviviridae family that has reemerged in recent years as a human pathogen with epidemic potential. To date, the ongoing epidemic in the Americas has led to tens of thousands of confirmed cases in Brazil alone (Pan American Health Organization Zika-Epidemiological Report, 2 March 2017). More concerning are the reports of severe neurological disorders such as Guillain-Barré syndrome and congenital Zika syndrome (microcephaly and other neurodevelopmental defects), which led the World Health Organization to declare the ZIKV epidemic as a Public Health Emergency of International Concern in 2016.
Keywords: Zika Virus.