[Source: Eurosurveillance, full page: (LINK). Abstract, edited.]
Eurosurveillance, Volume 22, Issue 31, 03 August 2017 / Rapid communication
Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016
A Carattoli 1 , L Villa 1 , C Feudi 1 2 , L Curcio 3 , S Orsini 3 , A Luppi 4 , G Pezzotti 3 , CF Magistrali 3
Author affiliations: 1. Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy; 2. Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany: 3. Istituto Zooprofilattico Sperimentale dell’Umbria e delle Marche, Perugia, Italy; 4. Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Reggio Emilia, Italy
Correspondence: Alessandra Carattoli (email@example.com)
Citation style for this article: Carattoli A, Villa L, Feudi C, Curcio L, Orsini S, Luppi A, Pezzotti G, Magistrali CF. Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016. Euro Surveill. 2017;22(31):pii=30589. DOI: http://dx.doi.org/10.2807/1560-7917.ES.2017.22.31.30589
Received:27 July 2017; Accepted:03 August 2017
A novel mcr colistin resistance gene was identified in a strain of Salmonella enterica, monophasic variant of serovar Typhimurium (4,5,12:i:- ), isolated from a pig at slaughter in Italy in 2013, and in Escherichia coli strains collected during routine diagnostic of post-weaning diarrhoea in pigs from Spain and Belgium in 2015 and 2016. Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Europe.
Keywords: Antibiotics; Drugs Resistance; Colistin; MCR4; Italy; Spain; Belgium; Pigs.