Novel #plasmid-mediated #colistin #resistance #mcr4 gene in #Salmonella and Escherichia coli, #Italy 2013, Spain and Belgium, 2015 to 2016 (@eurosurveillanc, abstract)

[Source: Eurosurveillance, full page: (LINK). Abstract, edited.]

Eurosurveillance, Volume 22, Issue 31, 03 August 2017  / Rapid communication

Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016

A Carattoli 1 , L Villa 1 , C Feudi 1 2 , L Curcio 3 , S Orsini 3 , A Luppi 4 , G Pezzotti 3 , CF Magistrali 3

Author affiliations: 1. Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy; 2. Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany: 3. Istituto Zooprofilattico Sperimentale dell’Umbria e delle Marche, Perugia, Italy; 4. Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Reggio Emilia, Italy

Correspondence: Alessandra Carattoli (alessandra.carattoli@iss.it)

Citation style for this article: Carattoli A, Villa L, Feudi C, Curcio L, Orsini S, Luppi A, Pezzotti G, Magistrali CF. Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016. Euro Surveill. 2017;22(31):pii=30589. DOI: http://dx.doi.org/10.2807/1560-7917.ES.2017.22.31.30589

Received:27 July 2017; Accepted:03 August 2017

 

Abstract

A novel mcr colistin resistance gene was identified in a strain of Salmonella enterica, monophasic variant of serovar Typhimurium (4,5,12:i:- ), isolated from a pig at slaughter in Italy in 2013, and in Escherichia coli strains collected during routine diagnostic of post-weaning diarrhoea in pigs from Spain and Belgium in 2015 and 2016. Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Europe.

Keywords: Antibiotics; Drugs Resistance; Colistin; MCR4; Italy; Spain; Belgium; Pigs.

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gimi69

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.

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