[Source: PLoS One, full page: (LINK). Abstract, edited.]
OPEN ACCESS / PEER-REVIEWED / RESEARCH ARTICLE
High prevalence of MRSA and ESBL among asylum seekers in the Netherlands
Sofanne J. Ravensbergen , Matthijs Berends, Ymkje Stienstra, Alewijn Ott
Published: April 25, 2017 / https://doi.org/10.1371/journal.pone.0176481
Migration is one of the risk factors for the spread of multidrug-resistant organisms (MDRO). The increasing influx of migrants challenges local health care systems. To provide evidence for both hospital hygiene measure and empirical antibiotic therapy, we analysed all cultures performed in asylum seekers between January 1st 2014 and December 31st 2015 for methicillin resistant Staphylococcus aureus (MRSA) and for multidrug-resistant Enterobacteriaceae (MDRE). We compared these with cultures from the Dutch patient population with risk factors for carriage of MDRO. A total of 7181 patients were screened for MRSA. 7357 S. aureus were isolated in clinical cultures. Of 898 screened asylum seekers, almost 10% were MRSA positive. Of 118 asylum seekers with S. aureus in clinical cultures almost 19% were MRSA positive. The general patient population had a 1.3% rate of MRSA in S. aureus isolates. A higher rate of Panton-Valentine leukocidin (PVL) positive strains (RR: 2.4; 95% CI: 1.6–3.4) was found in asylum seekers compared to the general patient population. In 33475 patients one or more Enterobacteriaceae were obtained. More than 21% of the asylum seekers were carrier of MDRE, most of them producing extended spectrum beta-lactamases (20.3%). 5.1% of the general patient population was MDRE carrier. It can be concluded that asylum seekers present with higher rate of MDRO compared to the general patient population. These results justify continued screening of asylum seekers to anticipate multidrug-resistant organisms during hospital care of patients.
Citation: Ravensbergen SJ, Berends M, Stienstra Y, Ott A (2017) High prevalence of MRSA and ESBL among asylum seekers in the Netherlands. PLoS ONE 12(4): e0176481. https://doi.org/10.1371/journal.pone.0176481
Editor: Herminia de Lencastre, Rockefeller University, UNITED STATES
Received: November 10, 2016; Accepted: April 11, 2017; Published: April 25, 2017
Copyright: © 2017 Ravensbergen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability: The data can be considered as politically sensitive information. Research data files are available upon request from Joline Stavasius (project coordinator research, including quality and data management, email@example.com).
Funding: The authors received no specific funding for this work.
Competing interests: The authors have declared that no competing interests exist.
Keywords: Migrants; Antibiotics; Drugs Resistance; Staphylococcus Aureus; MRSA; Enterobacteriaceae.