#Encephalomyelitis Associated With #Dengue Fever (JAMA Neurol., extract)

[Source: JAMA Neurology, full page: (LINK). Extract.]

Encephalomyelitis Associated With Dengue Fever


Yara Dadalti Fragoso, MD, MSc, PhD1; Joseph Bruno Bidin Brooks, MD, MSc1

JAMA Neurol. Published online September 12, 2016. doi:10.1001/jamaneurol.2016.1416



This case report describes a man in his 20s who was admitted with a clinical demyelination syndrome and a recent diagnosis of dengue fever.

A man in his 20s was referred to our multiple sclerosis reference center with a clinical demyelination syndrome. The patient was otherwise healthy until 2 weeks earlier, when he was diagnosed with dengue fever. For 5 days, the patient had a high temperature and a skin rash. The results of blood testing showed thrombocytopenia (70 × 103/μL platelets [to convert to × 109/L, multiply by 1]) and were IgM-positive for dengue fever. The patient started to recover from this viral infection, but 10 days later, he developed diplopia, optic neuritis, paraparesis, paresthesia, hyperreflexia in his lower limbs, abnormal proprioception, urinary incontinence, vertigo, and gait ataxia. The patient became bedridden and mentally confused and began sleeping excessively.


Keywords: Research; Dengue Fever; Encephalitis.


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Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.