#Developing #WHO rapid #advice #guidelines in the setting of a #publichealth #emergency (J Clin Epidemiol., abstract)

[Source: US National Library of Medicine, full page: (LINK). Abstract, edited.]

J Clin Epidemiol. 2016 Aug 31. pii: S0895-4356(16)30386-9. doi: 10.1016/j.jclinepi.2016.08.010. [Epub ahead of print]

Developing WHO rapid advice guidelines in the setting of a public health emergency.

Garritty CM1, Norris SL2, Moher D3.

Author information: 1Ottawa Methods Centre, Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Road, Box 201B, Ottawa, ON K1H 8L6, Canada; Translational Research in Biomedicine (TRIBE) Program, University of Split School of Medicine, Šoltanska 2, 21000 Split, Croatia. Electronic address: cgarritty@ohri.ca. 2World Health Organization, Av. Appia 20, CH-1211 Geneva 27, Switzerland. 3Ottawa Methods Centre, Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Road, Box 201B, Ottawa, ON K1H 8L6, Canada; School of Epidemiology, Public Health and Preventive Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Roger-Guindon Building, Ottawa, ON K1H 8M5, Canada.




We describe newly established guidance for guideline developers at the World Health Organization (WHO) on the process and procedures for developing a rapid advice guideline in the context of a public health emergency (e.g., the 2014 Ebola epidemic).


We based our approach on established rapid review methods, which were incorporated into existing WHO guideline development processes. Guidance was further informed by in-depth discussions of issues related to rapid guideline development with WHO staff (n = 6), who oversee the Organization’s response to emergencies.


We discuss criteria for considering if a rapid advice guideline is appropriate and feasible, and outline the roles of various contributors across the phases of development. Further, we describe the methods and steps involved in performing rapid reviews, which are more fluid and iterative than for a standard guideline process. In general, rapid advice guidelines involve a shorter timeline, narrower scope, and the use of abbreviated methods for the evidence review.


Important differences exist between developing a standard guideline and a rapid advice guideline. However, the core principles for WHO guidelines apply to rapid advice guidelines including minimizing bias, applying transparent processes and the use of explicit methods.

Copyright © 2016. Published by Elsevier Inc.

KEYWORDS: accelerated development; guideline; methodology; policy-making; public health; rapid reviews; recommendations

PMID: 27591906 DOI: 10.1016/j.jclinepi.2016.08.010

[PubMed – as supplied by publisher]

Keywords: Research; Abstracts; Public Health.


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Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.