[Source: Antimicrobial Agents and Chemotherapy, full page: (LINK). Abstract, edited.]
Plasmid with colistin resistance gene mcr-1 in ESBL-producing Escherichia coli strains isolated from pig slurry in Estonia
Age Brauer a, Kaidi Telling b, Mailis Laht c, Piret Kalmus d, Irja Lutsar b, Maido Remm a, Veljo Kisand c and Tanel Tenson c#
Author Affiliations: Institute of Molecular and Cell Biology, University of Tartu, Estonia a; Institute of Microbiology, University of Tartu, Estonia b; Institute of Technology, University of Tartu, Estonia c; Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences d
A plasmid carrying the colistine resistance gene mcr-1 was isolated from a pig slurry sample in Estonia. The gene was present on a 33 311 bp plasmid of IncX4 group. The mcr-1 is the only antibiotic resistance gene on the plasmid, the other genes coding mainly proteins involved in conjugative DNA transfer (taxA, taxB, taxC, trbM and the pilX operon). The plasmid, pESTMCR, was present in three phylogenetically very different Escherichia coli strains suggesting that it has high potential for horizontal transfer.
#Address correspondence to Tanel Tenson, email@example.com
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Keywords: Research; Abstracts; Antibiotics; Drugs Resistance; Colistin; MCR1; Estonia; Pigs; E. Coli.