#Plasmid with #colistin #resistance #gene #mcr1 in #ESBL-producing #Escherichia coli strains isolated from #pig #slurry in #Estonia (AAC, abstract)

[Source: Antimicrobial Agents and Chemotherapy, full page: (LINK). Abstract, edited.]

Plasmid with colistin resistance gene mcr-1 in ESBL-producing Escherichia coli strains isolated from pig slurry in Estonia

Age Brauer a, Kaidi Telling b, Mailis Laht c, Piret Kalmus d, Irja Lutsar b, Maido Remm a, Veljo Kisand c and Tanel Tenson c#

Author Affiliations: Institute of Molecular and Cell Biology, University of Tartu, Estonia a; Institute of Microbiology, University of Tartu, Estonia b; Institute of Technology, University of Tartu, Estonia c; Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences d



A plasmid carrying the colistine resistance gene mcr-1 was isolated from a pig slurry sample in Estonia. The gene was present on a 33 311 bp plasmid of IncX4 group. The mcr-1 is the only antibiotic resistance gene on the plasmid, the other genes coding mainly proteins involved in conjugative DNA transfer (taxA, taxB, taxC, trbM and the pilX operon). The plasmid, pESTMCR, was present in three phylogenetically very different Escherichia coli strains suggesting that it has high potential for horizontal transfer.



#Address correspondence to Tanel Tenson, tanel.tenson@ut.ee

Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Keywords: Research; Abstracts; Antibiotics; Drugs Resistance; Colistin; MCR1; Estonia; Pigs; E. Coli.


Published by

Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.